Researchers try multiple means to get high-quality membrane proteins for X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy studies. As much as 30% of human genes code for ...
Membrane proteins are sorted to the plasma membrane (PM) via Golgi-dependent trafficking. However, our recent studies challenged the essentiality of Golgi in the biogenesis of specific transporters.
The VLP platform can project membrane proteins in their natural conformation on the surface of virus-like particles, generating full-length transmembrane proteins well-tailored for immunization ...