Huang's group had previously found that mouse neurons producing human APOE4 release molecular signals that activate microglia. This time, they used the new mouse model to probe in more detail the ...

Once across, some of these travelers find themselves within the clutches of a specialized type of microglia, according to a preprint posted October 2 on bioRxiv. Through fluorescent labeling of the ...

To investigate, Kaji and colleagues hunted them down in the ApoE-Halo/5xFAD mouse brain with confocal microscopy and three-dimensional imaging. In addition to the usual large extracellular plaques, ...

Huang's group had previously found that mouse neurons producing human APOE4 release molecular signals that activate microglia ...

In a new study from Texas A & M University College of Medicine, researchers have used a nasal spray to target microglia and ...

But when APOE4 is expressed, microglia seem to start to cause inflammation, and misfolded proteins to form in the brain, ...

Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this ...