After they cross into the brain, some circulating proteins stir a subset of microglia. They boost the cells’ metabolism, phagocytosis, and antigen presentation. These microglia are in the hypothalamus ...

Image Credit: Axol Bioscience Ltd To evaluate the functional performance of the axoCells Microglia, Axol conducted various assays, such as phagocytosis, chemotaxis, and cytokine release ...

Microglia express tight junction molecule (CLDN5) to maintain BBB integrity in early phase and molecule for phagocytosis (CD68) to impair the BBB function in late phase of systemic inflammation.

Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the development and remodelling of the nervous system. Their shape varies depending on the ...