When miRNA acts as the guide for RNAi, only a short part of the molecule ... This often results in a 100 percent match between guide and target, with very low off-target activity. Additionally, siRNAs ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

In mammalian cells the miRNA molecule is incorporated into ... the SMARTpool products offer the “highest level of guaranteed silencing of gene and lowest chance of off-target effects.” ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

One strand of the mature miRNA duplex, known as the guide strand, is incorporated into the RNA-induced silencing complex (RISC). The RISC ... This complex regulatory network allows miRNAs to fine-tune ...