【导读】成纤维细胞样细胞是肿瘤微环境(TME)的重要组成部分,在肝细胞癌(HCC)进展中发挥着关键作用。ITGA5是恶性肿瘤中成纤维细胞样细胞的关键调节因子。11月21日,暨南大学曲辰研究团队在期刊《Molecular ...
Novel method identified protein degraders that target Pin1, a protein involved in pancreatic cancer development.
Gastrointestinal (GI) cancers are among the most common cancer types affecting millions worldwide with a poor survival rate ...
A defining feature of many cancers is genomic instability, which refers to the increased likelihood of acquiring mutations during cell division. These alterations can serve as potential biomarkers for ...
Researchers from Vrise Therapeutics Inc. and Vegen Therapeutics Pvt Ltd. presented preclinical data for VRTX-531, an allosteric inhibitor of ubiquitin carboxyl-terminal hydrolase 1 (USP1), being ...
In addition to studying the immune system, you will take pathology, microbiology and biochemistry units. In the second year, you will study the cellular and molecular basis of cancer and its therapy ...
In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to ...
(NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer ... AACR Symposium on Molecular Targets and ...