How does our nervous system operate so quickly and efficiently? The answer lies in a membranous structure called myelin. Aa Aa Aa All our activities — eating, walking, talking — are controlled ...
Conditional knock-out mice in which Myrf is knocked out in the OL lineage cells completely fail to develop CNS myelin and exhibit severe neurological symptoms, eventually prematurely dying. Recently, ...
The primary focus in the laboratory is on ion channels that regulate specification, migration and differentiation of these glial cells. The oligodendrocyte generates CNS myelin, which is essential for ...
Chronic loss of the protective myelin harms neurons. This damage leads to worsening disability in diseases such as MS that cause demyelination. However, it's still unclear how this process causes ...