The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, ...

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, ...

"I think it's fascinating that an aspect of how p14 ARF acts as a tumor suppressor is through immobilization of the liquid-like nucleolus and apparent inhibition of critical steps in ribosome ...

Through interaction with nucleophosmin, a protein abundant within the nucleolus that acts as director of the ribosome factory, p14 ARF becomes a spanner in the works of the nucleolus, disrupting ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

This occurs within the nucleolus, a membraneless compartment in the nucleus of cells responsible for ribosome production. In ...