Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into ...

Bone tissue is composed of cells, namely osteoblasts, osteoclasts and osteocytes, and an extracellular matrix comprising inorganic hydroxyapatite crystals and organic collagen.

osteoblasts are prevented from maturing to form bone tissue. In this study, osteoblast cells were isolated from transgenic ...

In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

The discovery of a key protein that blocks the activity of bone-forming cells could pave the way for new osteoporosis treatments, according to scientists. More than 3.5 million people are thought ...

However, when the protein CLEC14A is also present on the outside of the endothelial cell, osteoblasts are prevented from maturing to the point where they can form bone tissue. In this study ...