Indeed, IRF-8 exhibited a robust inhibitory role in osteoclastogenesis. These new data suggest that osteoclast differentiation involves an intimate balance between RANKL-driven positive regulators ...

OPG and RANKL Are Regulated by Systemic Hormones, Growth Factors, and Cytokines Cite this: Osteoprotegerin and its Ligand: A New Paradigm for Regulation of Osteoclastogenesis and Bone Resorption ...