When I was diagnosed with lung cancer, I didn’t want to receive chemotherapy, especially when I was a good candidate for ...
This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...
mRNA vaccines, pivotal in the fight against COVID-19, are now emerging as a promising innovation in cancer treatment. As ...
PD-L1 is a cell surface receptor expressed on both tumour and regulatory immune cells and functions as a checkpoint to inhibit T-cell function, while IDO1 is an enzyme involved in T-cell ...
Researchers have discovered that combining immunotherapy and chemotherapy can overcome treatment resistance in a subset of ...
特别是外周组织中活化的CD8+T细胞、CD4+T细胞和B细胞中[2]。PD-1有两个结合配体,PD-L1(B7-H1或CD274)和PDL2(B7-DC或CD273)。PD-L1表达于活化的T细胞、B细胞、巨 ...
Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic ...
After hours of company pushback, FDA's Oncologic Drugs Advisory Committee voted that the benefit of immunotherapy in low or ...
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