According to the results, tissue plasminogen activator (tPA) activates plasminogen to form plasmin, which cleaves the precursor of brain-derived neurotrophic factor (BDNF) to release the mature ...

IV tissue plasminogen activator (tPA) is a safe and effective therapy for acute ischemic stroke when administered within established time windows. The main complication from administration of tPA ...

While the use of recombinant tissue plasminogen activator in accordance to licensed criteria has continuously risen, off-label use is also frequent. In this review the most important reasons to ...

The Spurs announced the diagnosis on Wednesday. The Spurs organization had closed ranks around Popovich since he went ...

A clotting (ischemic) stroke occurs when clots block blood flow to the brain. In 1995, the U.S. Food and Drug Administration (FDA) approved the first clot-busting agent for ischemic strokes, named ...

For further clarification, consult your healthcare provider. This medication is an enzyme (tissue plasminogen activator (tPA)), prescribed for heart attack, stroke, and pulmonary embolism.