When tested in mice, the compound—named BBI-2779—shrank gastric tumors and prevented the cancer from developing resistance to another cancer drug. The results were published in Nature on Nov. 6.

Figure 2: Molecular and cellular changes in skin of wild-type and TNF-α –/– mice during tumor promotion. 'Tumor necrosis factor' might be considered an inappropriate name for a cytokine that ...

The Mouse Tumor Biology database (MTB) has been developed to provide electronic access to mouse tumor biology data. The primary focus of MTB is spontaneous and induced tumors in genetically ...