Ever griped about your height? Figuring out its origins hasn't been any easier for geneticists who are turning to high-throughput, genome-wide association studies for clues. At first glance, the ...

Glaucoma risk can be managed more effectively with the ability to use polygenic risk scores to identify individuals who can ...

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as ...

However, many of the common diseases exhibit a more complex inheritance pattern and are associated with mutations in multiple genes (in other words, these conditions are polygenic). As a result ...

Together with Michal Hledík, a recent ISTA graduate, and Professor Gašper Tkačik, Ružičková now proposed a model that might help to analyze "polygenic diseases," where many regions in the ...