In 1961 the structure of one protein, myoglobin, was known at 6 Å resolution and its 2 Å structure would soon be published. The structural determinations of hemoglobin and hen lysozyme were well ...

Protein structure and dynamics are intimately linked with biological activity. Understanding the physical basis for this activity requires knowledge of the equilibrium and kinetic properties of ...

With it he showed it was possible to reverse the protein-folding problem by designing a protein shape and then predicting the ...

Protein folding has been an ongoing problem for researchers since 1972. Christian Anfinsen speculated in his Nobel Prize acceptance speech in that year that the three-dimensional structure of a ...

HHMI researchers bring the arcane world of protein folding to the online gaming arena with the launch of “Foldit.” Multiplayer online gaming brings to mind fabulously successful titles, such as “World ...

Until now, researchers have focused their efforts on designing drugs to block CDC37’s role in protein folding by disrupting the way it interacts with HSP90. But this new research, carried out by ...

Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and ...

But now, AI systems are poised to dramatically accelerate this painstaking process. For decades, scientists puzzled over the ...

In protein folding studies, Adaptive CVgen has been applied across various proteins with multiple secondary structures, capturing dynamic folding processes without requiring parameter adjustments.