A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new ...

RNA splicing is a modification of the nascent ... splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and ...

Altered RNA processing is highly damaging to neurons, adding a new toxic component to the evolution of AD. Currently, the ...

We haven't been able to explain how the simple molecules that would've been floating around in the primordial waters of early ...

Fungal tRNA Splicing as a Paradigm of RNA Repair – Intron-containing tRNAs are widespread ... We recently solved a 2.2 Å crystal structure of the Candida Trl1 kinase domain in complex with GDP and Mg ...

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that ...

Defects in RNA splicing or mutations can lead to a wide variety of diseases, ranging from metabolic disorders to cancer. A point mutation occurs when a single nucleotide is erroneously inserted ...

A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the destruction of disease-causing mRNA. Achieving the opposite and stabilizing health-promoting mRNA is still ...

The intestinal microbiome is a highly complex ecosystem with thousands of different types of bacteria. Live and let live, ...

Since inosine is interpreted as guanosine (G) by the cellular machinery, A-to-I editing can alter codons, splicing sites ... provide a more comprehensive understanding of the complex interplay between ...