RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that ...

Altered RNA processing is highly damaging to neurons, adding a new toxic component to the evolution of AD. Currently, the ...

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new ...

Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly ...

Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, ...

Defects in RNA splicing or mutations can lead to a wide ... a crucial role in post-transcriptional modification (PTM), a process that occurs after transcription and precedes protein production.

This is a very labor intensive process, trying to track down a gene ... And so it could have been that this particular small RNA base-pairing to this mRNA of lin-14 gene and turning off production ...

Subsequently, the CRISPR–Cas13 system has emerged as a potential tool to identify and rectify errors in RNA sequences. CRISPR–Cas13 is a novel technology is specifically engineered for virus ...

The findings reveal how the absence of TRMT10A leads to a reduction in specific transfer RNA (tRNA) levels, disrupting protein synthesis in the brain and impairing synaptic structure and function.