引言近年来，RNA生物学的重要性愈发凸显，特别是在新型疫苗和基因调控技术的突破中，RNA分子展现了前所未有的潜力。然而，RNA的复杂三维结构依然是生命科学领域中最具挑战性的问题之一。其灵活的折叠和多样的构象意味着单凭实验手段难以全面揭示这些分子背后的 ...

Researchers have identified that G-quadruplexes promote harmful protein aggregation in neurodegenerative diseases. Blocking ...

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

This deep learning-based method utilizes an RNA language model to accurately predict RNA 3D structures. This method addresses the challenges of RNA's intrinsic structural flexibility and the ...

Recent findings indicate that the chirality of molecules, critical to life's structure, might not have been as fixed in early ...

编辑丨王多鱼排版丨水成文无限制的炎症可能会导致宿主组织损伤，甚至引发自身免疫疾病。Toll样受体（TLR）是免疫系统中重要的模式识别受体（PRR）之一，通过识别病原体相关分子模式来启动固有免疫反应。因此，必须精确地调控TLR及其下游信号通路，以防止免 ...

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of ...

Researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.