San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's ...

Ahead of their game against the Buffalo Bills, it’s time to release our San Francisco 49ers Week 13 predictions.

NFL analyst reports that the 49ers and Raiders are the top suitors for free agent quarterback Daniel Jones following his ...

The San Francisco 49ers are 5-6 after a brutal loss to the Green Bay Packers in Week 12. With the playoffs slipping away, ...

The offensive line of the San Francisco 49ers hasn't been too shabby this season. But that doesn't mean they can't use some ...

You can listen to the Bills vs. 49ers live on SiriusXM. The Bills broadcast can be found on channel 225, while 49ers fans ...

The San Francisco 49ers are reportedly hoping that quarterback Brock Purdy's shoulder injury isn't a long-term issue, but ...

San Francisco 49ers head coach Kyle Shanahan has offered an update on the injuries to Nick Bosa and Brock Purdy.

San Francisco 49ers general manager John Lynch appeared on Bay Area radio station KNBR on Friday morning to share the latest ...

The San Francisco 49ers are dealing with a handful of injuries following a disastrous Week 11 loss to the Seattle Seahawks. A ...

Kyle Shanahan announced that the 49ers rule out All-Pro defensive end Nick Bosa and starting quarterback Brock Purdy for ...

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...