[20] Here we show that inhibiting SirT1 gene expression in the liver and WAT is sufficient to recapitulate the cytokine elevations seen in rodent and human overnutrition, as well as to trigger ...

Alternatively, acetylation and SIRT1 may determine the gene specificity of FoxO as previously proposed 41. As outlined in the first part of this Review, FoxOs coordinate cell-cycle arrest ...

Our data show the anisotropic regulation of Ankrd2 gene expression in the diaphragm muscles occurs via two distinct mechanosensitive ... We have been interested in the physiologic role of Sirt1 in ...

Male offspring with the additional SIRT1 gene show lower body weight and attenuation of metabolic disorders due to obesity in mothers. Disclaimer: AAAS and EurekAlert! are not responsible for the ...

This breakthrough finding revealed a long-postulated ... Noninvasive Measurement of Gene Expression at Target Locations in the Brain Aug. 7, 2024 — Bioengineers have developed a noninvasive tool ...

Sinclair published a paper in 2012 showing that mice that do not have the SIRT1 gene do not receive the benefits of resveratrol. He produced similar results in yeast in a 2003 study. The problem ...

You can revise by clicking the links below. To brush up on your GCSE reproduction, the genome and gene expression knowledge, click on the link to your awarding body specific revision: ...

Ionising radiation includes gamma rays, X-rays and ultraviolet rays. The greater the dose of radiation a cell gets, the greater the chance of a mutation. Mutations could cause different genes to ...

Changes Upstream: RIPE Team Uses CRISPR/Cas9 to Alter Photosynthesis for the First Time June 7, 2024 — Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream ...

Ban Ki-moon of the Republic of Korea, the eighth Secretary-General of the United Nations, brings to his post 37 years of service both in Government and on the global stage. Freedom of expression ...

Gerry Baker is Editor at Large of The Wall Street Journal. His weekly column for the editorial page, “Free Expression,” appears in The Wall Street Journal each Tuesday. Mr. Baker is also host ...