Our results are consistent with a model whereby fast-folding proteins utilize a diffusion-collision mechanism, with the preorganization of one or more elements of secondary structure in the ...

Regular secondary structures, like alpha helices and beta sheets, form the fundamental scaffolding of protein architecture.

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for ...

Researchers developed MassiveFold, an enhanced AlphaFold version optimized for parallel processing, which accelerates protein ...

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, ...

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, including those involving the tumor suppressor protein p53, are widely studied ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...