Cytotoxic drugs and other emesis-stimulating agents form free radicals that activate enterochro-maffin cells, which release serotonin. The serotonin stimulates 5-HT 3 receptors located along the ...
The drug, called Cobenfy and developed by US pharma giant Bristol Myers Squibb, works differently from existing treatments, targeting the so-called cholinergic receptors, not the dopamine receptors.
Hormone therapy (also called hormonal therapy or endocrine therapy) slows or stops the growth of hormone-sensitive tumors by blocking the body’s ability to produce hormones or by interfering with the ...