Many companies use proprietary algorithms to design ... and antibodies that can be used to validate that siRNA-mediated gene silencing worked. In partnership with Dharmacon, Upstate also offers ...
By silencing specific genes in plants ... leading to undesired consequences. Careful design and validation of siRNA sequences, as well as the use of advanced algorithms and screening methods, can help ...
[43] Gene silencing techniques Description of mechanism Ref. siRNA The siRNA associates with RISC leading to unwinding of the dsRNA, sense strand of which is cleaved by Argonaut2 protein.