Nature2y
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
Figure 4: Short-term effect of THC on sphingomyelin hydrolysis, ceramide levels and ERK activity in C6.9 and C6.4 glioma cells. Figure 5: Long-term effect of THC on ceramide levels and ERK ...
Nature5y
Ceramide buds in
Cargo proteins that are destined for lysosomal degradation are first incorporated into intraluminal vesicles (ILVs), which form by the invagination of endosomes; this process turns endosomes into ...
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Scientists provide novel insights into the effects of high temperature on nutritional obesity
Metabolomic and lipidomic analyses of SMT indicated that HT promotes ceramide breakdown, leading to an increase in sphingomyelin and sphingosine. Further investigation revealed that the ...