In the 1930s, Muller was surprised to note that telomeres were strangely resistant to mutagenic X-rays. Why are the unique properties of these chromosomal "end caps" so important? Thus ...

Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...

The evidence supporting the relevance of replicative senescence of human cells and telomere biology to human cancer is now quite strong. The evidence linking replicative senescence to human aging ...

The ends of chromosomes, called telomeres, shorten with age. They function like a molecular clock for the cell. Premature shortening of these DNA sequences is the cause of genetic diseases: ...