【导读】化疗耐药是胃癌（GC）治疗失败的主要原因。然而，奥沙利铂（OXA）耐药的机制尚不明确。10月11日，中山大学研究团队在期刊《Advanced Science》上发表了研究论文，题为“Gastric Cancer Actively ...

The regulation and remodeling of the tumor microenvironment (TME) are closely associated with how cancers typically progress ...

Adhesive Interactions Influencing Metastases Integrins are the major extracellular matrix (ECM) receptors, and integrin-mediated adhesive interactions between tumor cells and the components of ...

Tumor cells influence stromal changes including remodeling of the ECM, and this changed stroma participates in tumorigenesis well before the tumor has begun to invade and disseminate. Gene ...

【导读】了解头颈部鳞状细胞癌（HNSCC）的侵袭和转移机制对于有效治疗至关重要，尤其是在转移性病例中。在这项研究中，团队分析了来自702,446个细胞的多中心批量测序和综合单细胞数据，鉴定了一种新的癌症相关成纤维细胞（CAF）亚型，称为分泌型卷曲相关 ...

2024年9月19日， 北京大学生命科学学院生物医学前沿创新中心（BIOPIC）张泽民院士团队在期刊《Cancer Cell ... 包括细胞外基质（ECM）的沉积和重塑 ...

Tumors are one of the most misunderstood diagnoses or conditions. While no one wants to be told they have one, many people don't realize that a tumor is nothing more than a clump of abnormal cells ...

Sep. 20, 2024 — Researchers have used a drug screening platform they developed to show that an antidepressant, currently on the market, kills tumor cells in the dreaded glioblastoma -- at least ...

This is an important piece of work that sheds light on our understanding of early lung development. There is solid evidence that there is a key new role for Svep1, which may be acting via FGF9. A more ...

A mediastinal tumor is a growth that occurs in the space inside the chest, near organs such as the heart and lungs. Some of these tumors may cause symptoms, but some may not. When mediastinal ...

"So I was freaking out." The next day, a specialist diagnosed their daughter not with spina bifida, but with a sacrococcygeal teratoma, a rare fetal tumor that forms from the baby’s tailbone.