retinal organoids with all the major retinal cell types. These technological advances offer an unparalleled opportunity to model human retinal development and disease, test potential therapeutic ...

USC researchers use 3D microscopy and genetically engineered viruses to visualize and distinguish specific retinal ganglion cell types (shown here in green) from other cells in the retina (purple).

In this study, Professor Bernier's team developed a method to coax stem cells into forming sheets of cells that recapitulate ...

After all, cells of the same type should be expected to behave similarly. "The question for us was: if the retinal ganglion cells behave differently, is it because they are integrated into ...

USC researchers use 3D microscopy and genetically engineered viruses to visualize and distinguish specific retinal ganglion ...

After all, cells of the same type should be expected to behave similarly. "The question for us was: if the retinal ganglion cells behave differently, is it because they are integrated into ...

It enables the precise ‘molecular dissection’ of the multiple cell types present within a complex tissue ... ongoing projects from my lab and collaborators which are applying scRNA-Seq to investigate ...

More information: Michael Housset et al, Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina, Developmental Cell (2024). DOI ...