These signalling systems operate beyond cell and tissue boundaries, but function as morphogens that are secreted from one cell or tissue type to activate surface receptors, signal transduction ...

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life.

Finally, pathways such as Wnt signaling are very complex and involve a number of different ligands, receptors and endogenous antagonists and the activation of distinct intracellular signaling ...

When he added the Wnt-coated beads to dishes in which embryonic stem cells were growing, the scientists could then watch individual cells that were close enough to a bead to receive a Wnt3a signal, ...

For many years, scientists have known that genetic variants, or differences in DNA code across people, play some role in ...

决定依据《国家自然科学基金项目科研不端行为调查处理办法》第五十条第一项、第四项和第四十四条第四项，取消全成国家自然科学基金项目评审专家资格3年（2024年4月9日至2027年4月8日），取消全成国家自然科学基金项目申请和参与申请资格2年（2024年4月9日至2026年4月8日），给予全成通报批评。

Dr. Gujral also works to develop better ways to screen potential cancer drugs. Noncanonical Wnt signaling pathway. Dr. Gujral’s lab explores how this pathway contributes to changes in cell state that ...

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a clinical-stage pharmaceutical company ...

Enrollment of the study's Phase 1 monotherapy dose escalation portion was completed in July 2024. ST316 is designed to ...

The regulation and remodeling of the tumor microenvironment (TME) are closely associated with how cancers typically progress ...

This useful study by Gao et al identifies Hspa2 as a heterogeneous transcript in the early embryo and proposes a plausible mechanism showing interactions with Carm1. The authors propose that ...