Alternatively, an inhibitor might suffer a loss-of-function mutation, lose its ability to regulate signalling and lose its functions as a tumour suppressor. Both types of change in Wnt signalling ...

Pen-N3 是一种 PDZ 肽。Pen-N3 通过识别散乱蛋白抑制Wnt/b-catenin 的信号传导。 多字母 H2N-Glu-Ile-Val-Leu-Trp-Ser-Asp-Ile-Pro-OH ...

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...