The work on secreted miRNA has led to extracellular vesicle-based delivery of small interfering RNA (siRNA) therapy. This white paper describes research undertaken by groups at SLiS of NJU ...

北京时间10月7日，瑞典卡罗琳斯卡医学院宣布，将2024年诺贝尔生理学或医学奖授予美国科学家维克托·安布罗斯(Victor Ambros)和加里·鲁夫坎(Gary Ruvkun)，以表彰他们发现了微小核糖核酸（microRNA，以下简称miRNA）及其在转录后基因调控中的作用。 众所周知，在新药蓬勃发展的今天，小核酸药物被认为是将带来“除小分子药和抗体药之外的第三次制药浪潮”的关键。随着诺贝尔奖花 ...

You can gain deeper understanding of expression patterns of small non-coding RNAs by using assays that retain spatial organization at single cell resolution. Traditional methods such as NGS, can ...