【导读】肝细胞癌（HCC）是全球最致命的癌症之一。许多研究表明，代谢重编程对于HCC的发展至关重要。脲循环中的限速酶——CPS1在正常肝细胞中是一种丰富的蛋白质，但在HCC中的系统性研究尚未进行。

mRNA和长链非编码RNA（lncRNA）都是近些年热门的生物标志物研发方向。二者在基因调控、疾病相关信号通路、以及免疫应答等生物学过程中都起着关键作用。 本次在线讲座中，我们将为您介绍如何通过便利、准确的real-time PCR，对生物信号通路和疾病相关的mRNA和 ...

First, the kit enables the user to amplify the mRNA and convert it to cDNA directly from a cell lysate, with no loss of RNA. Second, the linear RNA amplification step improves the sensitivity of ...

Nearly six months after lodging a similar complaint against Pfizer and BioNTech over the partners’ COVID shot Comirnaty, GSK ...

【导读】放疗是食管鳞状细胞癌(ESCC)的主要治疗手段，但由于癌细胞对放疗的耐药，其疗效仍然受到限制。lncRNA和m6A已被证明在肿瘤辐射抗性中发挥重要作用。然而，m6a修饰的lncRNA在食管鳞癌放疗耐药中的确切表现和作用尚不清楚。10月5日，西 ...

The study is a valuable addition to the field, showing how particulate matter may be acting via nociceptor neurons towards neutrophilic asthma exacerbations. The solid evidence for the role of a ...

mRNA vaccines have gained widespread attention for their crucial role in fighting the COVID-19 pandemic. Yet, even before the ...

A team of researchers at the University of Pennsylvania took a new approach, using mRNA technology to design a multipronged vaccine that targets several proteins that underlie C. difficile’s ...

RNA binding protein ZCCHC24 promotes tumorigenicity and forms a positive feedback loop with the transcription factor ZEB1 in ...

How does a COVID-19 mRNA vaccine work? COVID vaccines are now available. Some of the COVID-19 vaccines are mRNA vaccines, but what does this mean? mRNA vaccines are different from traditional ...

This valuable paper seeks to determine the role of endogenous CNS hemoglobin in protecting mitochondrial homeostasis in hypoxia. There is merit in the work, although it remains incomplete as there is ...