Recent publications analyzing the relationship between local free energy and siRNA efficiency 4,5 have demonstrated that mRNA target site secondary structure is of great importance for siRNA ...

Reporting in Nature, Kumar and colleagues have now developed a method to target small-interfering RNA (siRNA) to the CNS, providing a safe and non-invasive approach for the delivery of this new ...

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.