RNAi is activated by introducing double-stranded RNA homologous to the target gene transcript. The exogenous RNA is digested in to small interfering RNAs (siRNA), which bind a nuclease complex to form ...

Whilst COVID-19 has undoubtedly changed our day to day reality, the RNAi community is exploring the possibility of siRNA drugs to target highly conserved regions of coronavirus RNA. It is now more ...

Stable nucleic acid lipid particle formulations. Stable nucleic acid lipid particle formulations in systemic delivery Target siRNA and modification (yes/no) Animal model Ref. DSPC:Chol:PEG–C ...

Sirius Therapeutics today announced that preliminary data from its Phase 1 clinical trial of SRSD107, a next generation siRNA ...

In a study published in Cell Reports Physical Science on Nov. 25, a research team reported the development of an innovative ...

In a study published in Cell Reports Physical Science on Nov. 25, a research team led by Prof. CAI Lintao from the Shenzhen ...