Peak fluconazole concentrations of 16–32 µg/ml were reached in all patients. Mean concentrations above 16 µg/ml were maintained for 17.0 ± 8.0 h at an ultrafiltration rate of 1,000 ml/h, ...

Fluconazole 2mg/mL; soln for IV infusion. Fluconazole is a highly selective inhibitor of fungal CYP450 dependent enzyme lanosterol 14-α-demethylase. This enzyme functions to convert lanosterol to ...