The review synthesizes evidence showing that ayahuasca's effects involve a delicate balance between two serotonin receptor types: 5-HT2A and 5-HT1A. This dual action appears crucial for understanding ...
According to the partners, DSP-0038 combines serotonin 5-HT2A receptor antagonism and 5-HT1A receptor agonism – two well established targets for antipsychotic drugs – in a single small molecule.
The Pacalis team is a blend of industry and academic expertise, led by co-founder and Monash university alumnus Dr David Bibby as Chief Executive Officer, and co-founder Professor Chris Langmead, ...
Axovant turned its attention to another neuroscience drug – 5-HT2A receptor inverse agonist nelotanserin, licensed from Arena Pharma – but that failed a phase 2 study in REM sleep behaviour ...
Skip More from 5 Live... The 5 Live at 30 Yearbook How 5 Live reported on some of the biggest news and sport stories of the past 30 years. Eleanor Oldroyd: 30 years of "my radio family" Eleanor ...
noradrenergic and specific serotonin receptor antagonists, dopamine and norepinephrine reuptake inhibitors, along with newly introduced antidepressants (e.g., vilazodone and agomelatine).