Social determinants of health have a more pronounced effect on mortality among patients with acute myeloid leukemia (AML) who ...

By addressing these issues, we can ensure that all patients, regardless of their socioeconomic status, have the opportunity ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

Intranuclear transcription factor staining was then performed using anti-human RORγt, GATA-3, AHR, FoxP3 and T-bet fluorophore-labeled antibodies (20min at room temperature). Cells were then washed ...

Furthermore, vaccination resulted in sustained protection even under repeated monthly exposure to aerosolized allergen, as shown by alleviation of AHR and reduced levels of eosinophils in ...

Once inside, the T-cells attack all cancer cells that carry the recognized structure. The CAR-T cells developed by Hutter's team have an extra feature aimed at altering the microenvironment.

Dec. 5, 2024 — Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a ...

Called Vance, the global, multinational, randomised phase three trial, led by Singapore clinician-scientist Toh Han Chong, is the largest completed trial on T-cell therapy on any solid tumour.

A precancerous cell is a cell with certain abnormalities that makes it more likely to become cancerous. These abnormalities don't mean that it will become cancer—in fact, most don't—but the diagnosis ...

Dec. 5, 2024 — The fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive ... Dec. 6, 2024 — A single ...