This review summarizes the association between the disruption of the BBB and the activation of astrocytes in epilepsy via ...

Pericytes regulate vascular constriction. Within the brain-wide perivascular space, a polarized astrocyte phenotype with AQP4 expression is essential for the functioning of the glymphatic system.

The possible link between neuroinflammation and AQP4 was advertised with neuromyelitis optica (NMO), a demyelinating disease. NMO is a pathological condition characterized by abnormal signals most ...

As reviewed, AQP4 has a key role in the edema process, which may be followed by ADC changes in different brain pathologies. However, whether the presence of AQP4 is beneficial or detrimental seem ...

It has no specific family link. Astrocytes are a subtype of important cells that make up the majority of cells in the nervous system. They perform many functions including providing nutrients ...

Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a rare autoimmune disease, which is characterized by the immune system attacking astrocytes in the central nervous system ... and ...

The results revealed that this strain of mice exhibited significant seizure behaviors and epileptiform brain waves, loss of hippocampal and amygdala neurons, astrogliosis, decreased pericyte coverage, ...

Here we dissect the heterogeneity in metastasis-associated astrocytes using scRNAseq and report a population that blocks the antitumoral activity of infiltrating T cells. This pro-tumoral activity is ...

SC3M_pol_lesion_1 <- point.in.polygon(SC3M.x, SC3M.y, SC3M_SC_lesion_1_x, SC3M_SC_lesion_1_y) SC3M_pol_nonlesion_1 <- point.in.polygon(SC3M.x, SC3M.y, SC3M_SC ...