Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...

Missense mutations in the amyloid precursor protein (APP) and presenilin-1 (PSEN1) cause early-onset familial Alzheimer’s disease (FAD) and alter proteolytic production of secreted 38-to-43-residue ...

Arafi et al. present results of studies designed to better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP). This ...

The technology – called Antibody Transport Vehicle (ATV): Amyloid beta – can be used to help amyloid-targeting drugs cross the blood brain barrier (BBB) more effectively, say the partners.

The drugs attack so-called amyloid plaques in the brain. But how can we reliably and cost effectively diagnose the presence of amyloid plaques in patients who show up at memory clinics with slight ...

Immune cells thereby contribute to the crosstalk between the microbiota and the brain and influence the production and ...

The trial is evaluating im Eli Lilly and Company (NYSE: LLY) today announced positive results from the TRAILBLAZER-ALZ 6 Phase 3b study, showing a reduction in amyloid-related imaging ...

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Update: November 25, 2024 (05:00 AM ET): We’ve updated this Samsung One UI 7 hub with beta timeline details, a video showing the split notification shade/quick settings menu, and more details.

In addition, PBMC production of IL-2 was significantly decreased while TGFβ1 production was increased. Furthermore, PBMCs obtained during the treatment period produced significantly more BDNF and ...

The treatments for hyperthyroidism are different from those for hypothyroidism. One aims to stem the production of T3 and T4, while the other aims to replace thyroid hormones with synthetic or natural ...