These statements include, but are not limited to, statements regarding the combination potential for MALT1 and BTK inhibitors in models of B-cell malignancies, PD biomarkers related to LSD1 ...

Poster Presentations Title: Combining next-generation BTK and MALT1 inhibitors to enhance efficacy and therapeutic utility in B-cell malignancies Session Title: Combination therapies Catalog ...

Three sets of targets collectively account for a large proportion of current efforts in kinase inhibitor drug discovery. These are the receptor tyrosine kinases (for example, EGFR, ERBB2 ...

“As our precision-designed LSD1 and MALT1 inhibitors continue to progress towards the clinic, we are excited to share new preclinical data from both programmes,” said David Hallett, Ph.D., interim ...

The French pharma said it will pay $100 per share in cash for San Francisco-based Principia, which specialises in Bruton’s kinase (BTK) inhibitor drugs, after the deal was unanimously agreed by ...

Monoamine oxidase inhibitors (MAOIs) are the oldest class of antidepressants. Although they have largely been replaced by newer medications with fewer side effects, they are still used to treat some ...

Encompassing an area of about 8 square miles, Destin isn't a difficult city to maneuver. There are 13 public access points for visitors wanting to spend a day on Destin's clean white sand or in ...

Building on the existing Guides feature, Maps in iOS 18 lets you save places with a quick tap of the + button on their Maps listing. Saved places are accessible from the new Library menu ...

It's one thing to not be able to check Instagram or scroll through TikTok; it's quite another to be somewhere unfamiliar with no way to load Google Maps. As it happens, however, Google offers a ...

Her work has been featured on CNN, NBC, NPR, the BBC, Mashable and more. Google Maps and Google Earth are getting a handful of updates, including more imagery across popular and less visited ...

Extrapolating from these trends, it is plausible that some drug discovery programmes in the near future will profile every kinase inhibitor that is synthesized against most of the kinome.