Their study, published in Oncogene, explores how increased methylmalonic acid impairs the activation and effector functions of CD8+ T cells, immune cells that play a vital role in fighting cancer.
Moreover, in people with MS and subclinical neuroinflammation, CD8 + T cells in the peripheral blood and cerebrospinal fluid expressed genes associated with increased activation, antigen ...
MDNA11 is a next-generation IL-2 superkine designed to selectively stimulate effector immune cells (CD8 + T cells and NK cells) by enhancing affinity for IL-2Rβ (CD122) while avoiding IL-2Rα (CD25), ...