Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.

Scientists have discovered that the brain produces "guardian peptides" that maintain its immune balance, potentially offering new treatments for neuroinflammatory diseases like MS and Alzheimer's. The ...

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a ...

It's too late for Lenin, but the University of Pennsylvania's high-resolution MRI scan of a dead person's brain is full of detail. Ex vivo MRI of the brain provides remarkable advantages over in vivo ...

Synuclein is a protein predominantly associated with neurodegenerative disorders, where its accumulation and aggregation are critical markers of disease progression. In the context of brain aging, ...

Owing to progress in medicine and corollary increases in lifespan, dementia has become a public health concern, thus a primary focus for research. However, cognitive decline is not an inevitable ...

Opens in a new tab or window An alternate dosing plan for the anti-amyloid drug donanemab (Kisunla) reduced the risk of brain ...

Plasma biomarkers differ in adolescents with sport-related concussions and uninjured samples, justifying their use to understand concussion neuropathology.

A Wayne State University School of Medicine faculty member has been awarded a total of $2.3 million by the National Institute on Aging of the National institutes of Health for two new, concurrent ...

At the 2024 Educational Research and Innovations in Clinical and Health Sciences (ENRICH) Week poster session, Hunter “Caroline” Davies secured first place in the innovation category for her poster, ...

Researchers have discovered that the gut bacteria Klebsiella pneumoniae can migrate to the brain, leading to inflammation and ...

New high-resolution maps of the mouse brain provide researchers with valuable insights into brain development and offer a ...