Using X-ray crystallography and cryogenic electron microscopy, Twelve Bio’s University of Copenhagen founders showed that Cas12a recognizes DNA target sequences with exquisite specificity ...
At this time, the core can perform genome editing with S.p. Cas9 or A.s. Cas12a/Cpf1. The targeting will be done in embryos using microinjection ... For reagent purchases on project redesigns the core ...