"If there is a problem with DNA packaging, the cell quickly senses this issue. But instead of triggering a typical stress response, the cell responds by slowing down its cycle of growth and ...

She and her team found that this effect happens through an unusual stress response. “If there is a problem with DNA packaging, the cell quickly senses this issue. But instead of triggering a typical ...

Chemotherapy targets cancer cells by disrupting DNA replication and mitotic processes, despite side effects on healthy cells.

Cell-cycle progression in eukaryotic cells, including the decision to initiate DNA replication, is driven by cyclin-dependent kinases (CDKs). The catalytic subunit of CDK is only active as a ...

Genomic stability is critical for cellular function, however, in the central nervous system highly metabolically active differentiated neurons are challenged to maintain their genome over the ...

Department of Molecular Biology, Kyushu University Graduate School of Pharmaceutical Sciences, Fukuoka, Japan ...

Their engineered cells can insert distinctive bits of genetic material into their DNA. As the cells divide, those genetic bits turn into distinctive bar codes. The technology is also allowing ...

These compounds are specifically designed to inhibit the Topoisomerase II enzyme, a critical player in DNA replication and ...

Throughout the cell cycle, magnesium is essential for stabilizing chromatin assembly ... Thus, magnesium plays a crucial role in the DNA replication process and preservation of genome stability.

Nov. 27, 2024 — The food additive carrageenan (E 407) can be responsible for the development of chronic inflammatory bowel disease, ulcers, and increased blood sugar levels in animals ...