The concept of 'checkpoints' arose from the discovery of genes in budding yeast that are required for coordinating the progression of cell-cycle events when earlier processes have not been ...

Of the many cellular functions regulated by signal transduction proteins, one of the most critical is cell-cycle progression. Some cell-cycle regulatory proteins must commit suicide after they ...

Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

The precision of this process depends in large measure upon stringent regulatory mechanisms that couple DNA replication to cell cycle progression. Initiation must be triggered at the appropriate time ...

When looking at cells with a microscope, the length of different stages of the cell cycle can be estimated using the formula: \(\text{Length of time in phase}=\) \(\frac{\text{observed number of ...

By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies ...

A life cycle is the series of stages something passes through during its lifetime. We also use the term for things that are not living, like cell phones. The life cycle for anything you buy includes ...

This research investigates the molecular mechanisms by which SMAD2/3-SMYD2 and developmental transcription factors cooperate ...