Conclusion: Clonidine and dexmedetomidine may provide additional benefit in managing alcohol withdrawal by offering a different mechanism of action for targeting withdrawal symptoms. Based on ...

The earliest studies of clonidine in the treatment of alcohol withdrawal were limited by the use of concomitant medications. Bjorkqvist et al. evaluated the efficacy of a clonidine taper ...

Because the FDA does not require any understanding of the mechanism by which a drug acts, it could be tempting to move into clinical trials without this knowledge. However, this may set the stage ...

The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...