引言在大脑的微观世界中，隐藏着人类智慧、感知与情感的奥秘。然而，这一复杂结构的发育和功能如何受到遗传变异的影响，仍是研究人员长期探讨的谜题。随着多能干细胞（pluripotent stem cells, ...

By combining morphological and single-cell level gene expression analyses, a team of researchers led by Professor Jun ...

LaNoce et al. described the use of human iPSC-based forebrain organoids as models of human early cortical development to explore the effect of the INSTIs dolutegravir (DTG) and RAL. Previously, this ...

However, the heterogeneity and low reproducibility of organoids present challenges to their scalable production, limiting their practical application in clinical trials and drug development processes.

cEpilepsy Genetics Program, Department of Neurology, Boston Children's Hospital, Boston, MA, USA dDepartment of Neurology, Harvard Medical School, Boston, MA, USA ...