BOSTON, Nov. 07, 2024 (GLOBE NEWSWIRE) -- Monte Rosa Therapeutics, Inc. (Nasdaq: GLUE), a clinical-stage biotechnology company developing novel molecular glue degrader (MGD)-based medicines, today ...

This valuable study uses robust time-dependent microscopy assays to show that during HIV-1 infection, the viral accessory protein Vif causes cell cycle arrest during metaphase and not G2/M as ...

Within specific indications, CID-078 single agent activity was correlated with RB1 mutation, high E2F target, or G2M checkpoint hallmark pathway scores ... with dual cyclin A and B RxL inhibitory ...

Get article recommendations from ACS based on references in your Mendeley library. Pair your accounts. Export articles to Mendeley Get article recommendations from ACS based on references in your ...

They examined how MZ1 was able to hold onto target protein Brd4 BD2 and direct it toward UBE2R1, a member of the ubiquitin-conjugating enzyme family, demonstrating the proficiency of MZ1 to position ...

Career readiness—and especially the somewhat amorphous concept of career pathways—has gained momentum over the past several years ... The Comprehensive Local Needs Assessment required by the Carl D.

Experts agree vitamin D is the one supplement we should all be taking during autumn and winter in the UK. This is because vitamin D plays a key role in immune and bone health, and between October and ...

NEDD4 promoted ubiquitination degradation of FLRT2 protein. NEDD4 counteracted the inhibitory effects of ... RT-qPCR was performed using SYBR Green Mix (TOYOBO, Japan) with primers for FLRT2, OCT4, ...

With the discovery that vitamin D regulates the expression of an important antimicrobial peptide gene, exciting research findings are revealing and characterizing new pathways regulated by vitamin ...

This cover highlights the article Elucidating the Assembly of Gas Vesicles by Systematic Protein-Protein Interaction Analysis by Manuel Iburg, Andrew P. Anderson, George J. Lu and colleagues. Gas ...