Ethanol-precipitate the DNA before ligation to concentrate the sample and remove salts that can interfere with ligation. The amount of vector obtained is usually sufficient to perform two 260-ng ...

Nov. 7, 2024 — Researchers have used ancient DNA to challenge long-held interpretations of the people of Pompeii. Contrary to physical appearances, the DNA evidence revealed unexpected ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

DNA sequencing is any chemical, enzymatic or technological procedure for determining the linear order of nucleotide bases in DNA. Sanger sequencing by replicative synthesis in the presence of ...

Last year, Coskun and his team introduced a new study in “single cell spatial metabolomics,” which explores the distribution ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...