This folate-trapping mechanism causes the death of the MTHFD2-expressing cancer cells only. Moreover, targeting nuclear MTHFD2 interferes with its DNA damage repair functions (Fig. 1) in an ...

It also plays an important role in DNA synthesis and repair. What is the difference between folic acid and folate? Folic acid is a synthetic form of folate that is commonly found in supplements ...

Also known as vitamin B9, folate is a crucial nutrient required for DNA synthesis, red blood cell creation, and the healthy development of a fetus. While a wide variety of foods include folate ...