Viral techniques work by introducing defective genes at random into the marmoset genome, providing researchers with a powerful tool to investigate the intricate mechanisms underlying certain diseases.

Generally, a single functioning copy of a gene is sufficient to ensure normal function even when the second copy is defective. Under this two-hit model, Brugge says, one normal copy of BRCA1 ought ...

A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...

CRISPR-based gene-editing tools are being developed to correct specific defective sections of the genome to cure inherited genetic diseases, with some applications already in clinical trials. However, ...