However, there are some promising treatments in early trials that target GPR6, which is abundant in some dopaminergic neurons ...
low doses of caffeine prevent the process of activation of the mesolimbic dopaminergic pathway by alcohol through a mechanism of action that involves specific receptors and alcohol’s metabolism ...
According to GlobalData’s Drugs Database, the schizophrenia market remains dominated by dopamine-targeted mechanisms, such as ...
Interestingly, D 1/5 receptor activation increases striatal ... D 1/5 agonist administration was an indirect effect of dopaminergic influences on the activity of nNOS-containing interneurons.
Destruction of the ascending dopaminergic pathway, blocking of dopamine receptors by drugs, inhibition of dopamine synthesis, or prevention of dopamine storage has been shown to induce akinesia on ...
Loss of dopaminergic neurons in the substantia nigra ... The neurons of the direct output pathway have D1 dopamine receptors on their cell bodies and localize dynorphin and substance P.
His work indicates that this effect is mediated by activation of dopamine receptors present on the macrophage surface ... changes in dopamine levels induced by drug abuse or the use of dopaminergic ...
Bromocriptine activates post-synaptic dopamine receptors. The dopaminergic neurons in the tuberoinfundibular process modulate the secretion of prolactin from the anterior pituitary by secreting a ...